Article
Functional 5' UTR motif discovery with LESMoN: Local Enrichment of Sequence Motifs in biological Networks.
Nucleic acids research - 13 Oct 2017
Lavallée-Adam Mathieu, Cloutier Philippe, Coulombe Benoit, Blanchette Mathieu
Abstract excerpt
Biological networks are rich representations of the relationships between entities such as genes or proteins and have become increasingly complete thanks to various high-throughput network mapping experimental approaches. Here, we propose a method to use such networks to guide the search for functional sequence motifs. Specifically, we introduce Local Enrichment of Sequence Motifs in biological Networks (LESMoN),...
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