Article
DNA-Microarray-based Genotyping of Clostridium difficile.
BMC microbiology - 5 Aug 2015
Gawlik Darius, Slickers Peter, Engelmann Ines, Müller Elke, Lück Christian, Friedrichs Anette, Ehricht Ralf, Monecke Stefan
Abstract excerpt
BACKGROUND: Clostridium difficile can cause antibiotic-associated diarrhea and a possibility of outbreaks in hospital settings warrants molecular typing. A microarray was designed that included toxin genes (tcdA/B, cdtA/B), genes related to antimicrobial resistance, the slpA gene and additional variable genes. RESULTS: DNA of six reference strains and 234 clinical isolates from South-Western and Eastern Germany...
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