Article
Array comparative hybridisation reveals a high degree of similarity between UK and European clinical isolates of hypervirulent Clostridium difficile.
BMC genomics - 21 Jun 2010
Marsden Gemma L, Davis Ian J, Wright Victoria J, Sebaihia Mohammed, Kuijper Ed J, Minton Nigel P
Abstract excerpt
BACKGROUND: Clostridium difficile is a Gram-positive, anaerobic, spore-forming bacterium that is responsible for C. difficile associated disease in humans and is currently the most common cause of nosocomial diarrhoea in the western world. This current status has been linked to the emergence of a highly virulent PCR-ribotype 027 strain. The aim of this work was to identify regions of sequence divergence that may...
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