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Article

Multilocus sequence analysis and comparative evolution of virulence-associated genes and housekeeping genes of Clostridium difficile.

Microbiology (Reading, England) - 1 Oct 2005

Lemée Ludovic, Bourgeois Ingrid, Ruffin Elodie, Collignon Anne, Lemeland Jean-François, Pons Jean-Louis

Abstract excerpt

A multilocus sequence analysis of ten virulence-associated genes was performed to study the genetic relationships between 29 Clostridium difficile isolates of various origins, hosts and clinical presentations, and selected from the main lineages previously defined by multilocus sequence typing (MLST) of housekeeping genes. Colonization-factor-encoding genes (cwp66, cwp84, fbp68, fliC, fliD, groEL and slpA), toxin...

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Identifiers

PMID: 16207902
DOI: 10.1099/mic.0.28155-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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