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Article

AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes.

Schizophrenia bulletin - 1 Jan 2016

Peltola Marjaana A, Kuja-Panula Juha, Liuhanen Johanna, Võikar Vootele, Piepponen Petteri, Hiekkalinna Tero, Taira Tomi, Lauri Sari E, Suvisaari Jaana, Kulesskaya Natalia, Paunio Tiina, Rauvala Heikki

Abstract excerpt

The enormous variability in electrical properties of neurons is largely affected by a multitude of potassium channel subunits. Kv2.1 is a widely expressed voltage-dependent potassium channel and an important regulator of neuronal excitability. The Kv2.1 auxiliary subunit AMIGO constitutes an integral part of the Kv2.1 channel complex in brain and regulates the activity of the channel. AMIGO and Kv2.1 localize to...

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Source

Open in PubMed Open full text

Identifiers

PMID: 26240432
DOI: 10.1093/schbul/sbv105
PMCID: PMC4681558

Genes

KCNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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