SufB intein of Mycobacterium tuberculosis as a sensor for oxidative and nitrosative stresses

Abstract excerpt

Inteins are mobile genetic elements that self-splice at the protein level. Mycobacteria have inteins inserted into several important genes, including those corresponding to the iron-sulfur cluster assembly protein SufB. Curiously, the SufB inteins are found primarily in mycobacterial species that are potential human pathogens. Here we discovered an exceptional sensitivity of Mycobacterium tuberculosis SufB intein...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antibiotic Resistance in Bacteria
• Share to RNA and protein synthesis mechanisms
• Share to Tuberculosis Research and Epidemiology