Article
Morphological analysis of Francisella novicida epithelial cell infections in the absence of functional FipA.
Cell and tissue research - 1 Feb 2016
Lo Karen Y, Visram Shyanne, Vogl A Wayne, Shen Chiao Ling Jennifer, Guttman Julian A
Abstract excerpt
Francisella novicida is a surrogate pathogen commonly used to study infections by the potential bioterrorism agent, Francisella tularensis. One of the primary sites of Francisella infections is the liver where >90% of infected cells are hepatocytes. It is known that once Francisella enter cells it occupies a membrane-bound compartment, the Francisella-containing vacuole (FCV), from which it rapidly escapes to...
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