Article
Genome-wide association study identifies SNPs in the MHC class II loci that are associated with self-reported history of whooping cough.
Human molecular genetics - 15 Oct 2015
McMahon George, Ring Susan M, Davey-Smith George, Timpson Nicholas J
Abstract excerpt
Whooping cough is currently seeing resurgence in countries despite high vaccine coverage. There is considerable variation in subject-specific response to infection and vaccine efficacy, but little is known about the role of human genetics. We carried out a case-control genome-wide association study of adult or parent-reported history of whooping cough in two cohorts from the UK: the ALSPAC cohort and the 1958...
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