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Article

Biochemical nature of Russell Bodies.

Scientific reports - 30 Jul 2015

Mossuto Maria Francesca, Ami Diletta, Anelli Tiziana, Fagioli Claudio, Doglia Silvia Maria, Sitia Roberto

Abstract excerpt

Professional secretory cells produce and release abundant proteins. Particularly in case of mutations and/or insufficient chaperoning, these can aggregate and become toxic within or amongst cells. Immunoglobulins (Ig) are no exception. In the extracellular space, certain Ig-L chains form fibrils causing systemic amyloidosis. On the other hand, Ig variants lacking the first constant domain condense in dilated...

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Identifiers

PMID: 26223695
DOI: 10.1038/srep12585
PMCID: PMC4649990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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