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Article

The role of Pannexin gene variants in schizophrenia: systematic analysis of phenotypes.

European archives of psychiatry and clinical neuroscience - 1 Aug 2016

Gawlik Micha, Wagner Martin, Pfuhlmann Bruno, Stöber Gerald

Abstract excerpt

Pannexins are a group of brain-expressed channel proteins thought to be regulators of schizophrenia-linked pathways including glutamate release, synaptic plasticity and neural stem proliferation. We got evidence for linkage of a catatonic phenotype to the PANX2 locus in a family study. Aim of our study was to evaluate the role of Pannexins in schizophrenia and clinical phenotypes, particularly with regard to...

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Source

Identifiers

PMID: 26223428
DOI: 10.1007/s00406-015-0619-8

Genes

PANX2
PANX1
PANX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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