Article
Identification of the semaphorin receptor PLXNA2 as a candidate for susceptibility to schizophrenia.
Molecular psychiatry - 1 May 2006
Mah S, Nelson M R, Delisi L E, Reneland R H, Markward N, James M R, Nyholt D R, Hayward N, Handoko H, Mowry B, Kammerer S, Braun A
Abstract excerpt
The discovery of genetic factors that contribute to schizophrenia susceptibility is a key challenge in understanding the etiology of this disease. Here, we report the identification of a novel schizophrenia candidate gene on chromosome 1q32, plexin A2 (PLXNA2), in a genome-wide association study using 320 patients with schizophrenia of European descent and 325 matched controls. Over 25,000 single-nucleotide...
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