Article
Splitting schizophrenia: periodic catatonia-susceptibility locus on chromosome 15q15.
American journal of human genetics - 1 Nov 2000
Stöber G, Saar K, Rüschendorf F, Meyer J, Nürnberg G, Jatzke S, Franzek E, Reis A, Lesch K P, Wienker T F, Beckmann H
Abstract excerpt
The nature of subtypes in schizophrenia and the meaning of heterogeneity in schizophrenia have been considered a principal controversy in psychiatric research. We addressed these issues in periodic catatonia, a clinical entity derived from Leonhard's classification of schizophrenias, in a genomewide linkage scan. Periodic catatonia is characterized by qualitative psychomotor disturbances during acute psychotic...
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