Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Does the presenilin 2 gene predispose to schizophrenia?

Schizophrenia research - 1 Apr 2009

Zhang Juan, Chen Jun, Xu Qi, Shen Yan

Abstract excerpt

Presenilins are a group of proteins playing an important role in the Notch, ErbB4 and Wnt signaling pathways possibly associated with schizophrenia. The gene coding for presenilin 2 (PSEN2) is located on 1q42 and adjacent to a balanced translocation t (1; 11) (q42; q14.3) that was found to co-segregate within family members of patients with schizophrenia. We thus hypothesized that PSEN2 may contribute to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Presenilin-2
Share to Asian People
Share to Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression

Share to Genome-Wide Association Study

Share to Haplotypes

Share to Psychiatric Status Rating Scales

Share to Schizophrenia

Source

Identifiers

PMID: 19232479
DOI: 10.1016/j.schres.2009.01.013

Genes

PSEN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Does the presenilin 2 gene predispose to schizophrenia?PMID 19232479Read ↗

Identification of the semaphorin receptor PLXNA2 as a candidate for susceptibility to schizophrenia.Semantic proximity Read ↗

Positive association of the human STON2 gene with schizophrenia.Semantic proximity Read ↗

DEGS2 polymorphism associated with cognition in schizophrenia is associated with gene expression in brain.Semantic proximity Read ↗

A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia.Semantic proximity Read ↗

The role of Pannexin gene variants in schizophrenia: systematic analysis of phenotypes.Semantic proximity Read ↗

The rs11191580 variant of the NT5C2 gene is associated with schizophrenia and symptom severity in a South Chinese Han population: evidence from GWAS.Semantic proximity Read ↗

Neuregulin-1 (NRG-1) and its susceptibility to schizophrenia: a case-control study and meta-analysis.Semantic proximity Read ↗

Association of haplotypes spanning <i>PDZ-GEF2</i>, <i>LOC728637</i> and <i>ACSL6</i> with schizophrenia in Han ChineseSemantic proximity Read ↗

Gap junction coding genes and schizophrenia: a genetic association study.Semantic proximity Read ↗

No evidence for association between NOTCH4 and schizophrenia in a large family-based and case-control association analysis.Semantic proximity Read ↗

Is NOTCH4 associated with schizophrenia?Semantic proximity Read ↗

Association of RGS2 and RGS5 variants with schizophrenia symptom severity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.