Article
The role of the CCR5 Delta32 polymorphism in abdominal aortic aneurysms.
International journal of immunogenetics - 1 Aug 2009
Sandford B, Bown M, London N, Sayers R
Abstract excerpt
BACKGROUND: C-C chemokine receptor 5 (CCR5) is involved in the regulation of the inflammatory response. Abdominal aortic aneurysms (AAA) may arise as the result of a chronic inflammatory process which is influenced by genetic predisposition. The CCR5 gene is associated with a 32 base pair deletion (the Delta32 polymorphism). The aim of this study was to investigate the role of the CCR5 Delta32 polymorphism in the...
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