Article
Mining for novel tumor suppressor genes using a shortest path approach.
Journal of biomolecular structure & dynamics - 1 Jan 2016
Chen Lei, Yang Jing, Huang Tao, Kong Xiangyin, Lu Lin, Cai Yu-Dong
Abstract excerpt
Cancer, being among the most serious diseases, causes many deaths every year. Many investigators have devoted themselves to designing effective treatments for this disease. Cancer always involves abnormal cell growth with the potential to invade or spread to other parts of the body. In contrast, tumor suppressor genes (TSGs) act as guardians to prevent a disordered cell cycle and genomic instability in normal...
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