Identification of hepatocellular carcinoma related genes with <i>k</i> -th shortest paths in a protein–protein interaction network

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide and one of the deadliest cancers in Asia. But at present, effective targets for HCC clinical therapy are still limited. The "guilt by association" rule suggests that interacting proteins share the same or similar functions and hence may be involved in the same pathway. This assumption can be used to identify disease related genes...

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