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Impact of HER2 codon 655 polymorphism and expression of HER2 and HER3 in non small cell lung cancer patients.

Wiener medizinische Wochenschrift (1946) - 1 Aug 2015

Ananiev Julian, Aleksandrova Elina, Skerleva Desislava, Gulubova Maya, Chokoeva Anastasiya, Lotti Torello, Wollina Uwe, Tchernev Georgi, Kontić Milica, Stojšić Jelena

Abstract excerpt

The aim of the study was to assess the expression and significance of HER2 and HER3, and Ile/Val single nucleotide polymorphism (SNP) of HER2 in lung cancer patients. Thirty seven cases of lung cancer were investigated immunohistochemically for HER2 and HER3 expression. PCR followed by restriction fragment length polymorphism (RFLP) was used to analyze the presence of HER-2 SNP at codon 655 in 20 samples. The...

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PMID: 26208475
DOI: 10.1007/s10354-015-0366-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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