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The influence of HER2 genotypes as molecular markers on breast cancer outcome.

DNA and cell biology - 1 Oct 2008

Mutluhan Hicran, Akbas Etem, Erdogan Nazan Eras, Soylemez Fatma, Senli Mehmet Siddik, Polat Ayse, Helvaci Ilter, Seyrek Ertugrul

Abstract excerpt

Alterations of the human epidermal growth factor receptor 2 (HER2) protooncogene have been implicated in the carcinogenesis and prognosis of breast cancer. A polymorphism has been identified at codon 655 (ATC/isoleucine to GTC/valine [I655V]) in the transmembrane domain-coding region of this gene, which may be associated with the risk of breast cancer. In this study we aimed to determine whether the risk of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18721072
DOI: 10.1089/dna.2007.0702

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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