Article
Glioma Association and Balancing Selection of ZFPM2.
PloS one - 1 Jan 2015
Tsang Shui-Ying, Mei Lingling, Wan Weiqing, Li Jun, Li Yi, Zhao Cunyou, Ding Xiaofan, Pun Frank W, Hu Xiaoxia, Wang Jianmin, Zhang Junyi, Luo Rongcheng, Cheung Siu-Tim, Leung Gilberto K K, Poon Wai-Sang, Ng Ho-Keung, Zhang Liwei, Xue Hong
Abstract excerpt
ZFPM2, encoding a zinc finger protein and abundantly expressed in the brain, uterus and smooth muscles, plays important roles in cardiac and gonadal development. Abnormal expression of ZFPM2 in ovarian tumors and neuroblastoma has been reported but hitherto its genetic association with cancer and effects on gliomas have not been studied. In the present study, the hexamer insertion-deletion polymorphism...
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