Article
A new risk locus in the ZEB2 gene for schizophrenia in the Han Chinese population.
Progress in neuro-psychopharmacology & biological psychiatry - 3 Apr 2016
Khan Raja Amjad Waheed, Chen Jianhua, Wang Meng, Li Zhiqiang, Shen Jiawei, Wen Zujia, Song Zhijian, Li Wenjin, Xu Yifeng, Wang Lin, Shi Yongyong
Abstract excerpt
The ZEB2 gene encodes the Zinc Finger E-box binding protein. As a key regulator of epithelial mesenchymal differentiation, ZEB2 plays an important role in the pathogenesis of cancer, and its high level expression has been observed in glioma patients. Different mutations in this gene have been identified in patients with Mowat-Wilson syndrome. A previous genome-wide association study (GWAS) of schizophrenia...
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