Article
KIR genes and their human leukocyte antigen ligands in the progression to cirrhosis in patients with chronic hepatitis C.
Human immunology - 1 Nov 2011
Marangon Amanda Vansan, Silva Giovanni Faria, de Moraes Camila Fernanda Verdichio, Grotto Rejane Maria Tomasini, Pardini Maria Inês de Moura Campos, de Pauli Dayse Sousa, Sell Ana Maria, Visentainer Jeane Eliete Laguila, Moliterno Ricardo Alberto
Abstract excerpt
Natural killer (NK) cells play pivotal roles in immune responses against infection with viruses, such as hepatitis C virus (HCV), and killer cell immunoglobulin-like receptors (KIRs) are related to the activation and inhibition of NK cells. The aim of this study was to investigate the possibility that KIR genes and their human leukocyte antigen (HLA) ligands influence progression to cirrhosis in patients infected...
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