Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized mice

24 Jul 2015

Abstract excerpt

Experimental studies of Plasmodium parasites that infect humans are restricted by their host specificity. Humanized mice offer a means to overcome this and further provide the opportunity to observe the parasites in vivo. Here we improve on previous protocols to achieve efficient double engraftment of TK-NOG mice by human primary hepatocytes and red blood cells. Thus, we obtain the complete hepatic development of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug-Induced Hepatotoxicity and Protection
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26205537
DOI: 10.1038/ncomms8690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized micePMID 26205537Read ↗

Modeling malaria in humanized mice: opportunities and challengesSemantic proximity Read ↗

Plasmodium vivax Liver Stage Development and Hypnozoite Persistence in Human Liver-Chimeric MiceSemantic proximity Read ↗

Plasmodium falciparum infection and exoerythrocytic development in mice with chimeric human liversSemantic proximity Read ↗

Complete Plasmodium falciparum liver-stage development in liver-chimeric miceSemantic proximity Read ↗

New horizons for studying human hepatotropic infectionsSemantic proximity Read ↗

Development of an Ectopic huLiver Model for <i>Plasmodium</i> Liver Stage InfectionSemantic proximity Read ↗

Global gene expression of human malaria parasite liver stages throughout intrahepatocytic developmentSemantic proximity Read ↗

Of men in mice: the success and promise of humanized mouse models for human malaria parasite infectionsSemantic proximity Read ↗

Development of Plasmodium falciparum liver-stages in hepatocytes derived from human fetal liver organoid culturesSemantic proximity Read ↗

Quantitative isolation and in vivo imaging of malaria parasite liver stages.Semantic proximity Read ↗

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized MiceSemantic proximity Read ↗

Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malariaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.