Article
The pathological and molecular but not clinical phenotypes are maintained after second passage of experimental atypical bovine spongiform encephalopathy in cattle.
BMC veterinary research - 2 Oct 2014
Konold Timm, Phelan Laura J, Clifford Derek, Chaplin Melanie J, Cawthraw Saira, Stack Michael J, Simmons Marion M
Abstract excerpt
BACKGROUND: Atypical bovine spongiform encephalopathies (BSEs), classified as H-type and L-type BSE based on the Western immunoblot profiles, are naturally occurring diseases in cattle, which are phenotypically different to classical BSE. Transmission studies in cattle using the intracerebral route resulted in disease where the phenotypes were maintained irrespective of BSE type but clinically affected cattle...
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