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Article

Dynamics of immunoglobulin sequence diversity in HIV-1 infected individuals.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Sept 2015

Hoehn Kenneth B, Gall Astrid, Bashford-Rogers Rachael, Fidler S J, Kaye S, Weber J N, McClure M O, Kellam Paul, Pybus Oliver G

Abstract excerpt

Advances in immunoglobulin (Ig) sequencing technology are leading to new perspectives on immune system dynamics. Much research in this nascent field has focused on resolving immune responses to viral infection. However, the dynamics of B-cell diversity in early HIV infection, and in response to anti-retroviral therapy, are still poorly understood. Here, we investigate these dynamics through bulk Ig sequencing of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26194755
DOI: 10.1098/rstb.2014.0241
PMCID: PMC4528418

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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