Article
Paraoxonase 1 genotype-phenotype correlation in patients with metabolic syndrome.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2015
Ciumărnean Lorena, Dronca Eleonora, Vesa Ştefan Cristian, Sâmpelean Dorel, Buzoianu Anca Dana, Achimaş-Cadariu Andrei
Abstract excerpt
The aim of the study was to investigate the influence of three single nucleotide polymorphisms (SNPs) (-108C>T, -162A>G and -909G>C) from the promoter region of paraoxonase 1 (PON1) gene on the enzyme activity, in patients with metabolic syndrome (MS). The study group consisted of 61 individuals with MS and the control group of 73 individuals without MS, matched for age and gender. For each individual, clinical...
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