Article
Paraoxonase phenotype distribution in a healthy Iranian population.
Basic & clinical pharmacology & toxicology - 1 Aug 2007
Sepahvand Farideh, Shafiei Massoumeh, Ghaffari Seyed Mahmood, Rahimi-Moghaddam Parvaneh, Mahmoudian Massoud
Abstract excerpt
Human serum paraoxonase (PON1) is a high-density lipoprotein-associated esterase that protects against organophosphate neurotoxicity, and is proposed to play a role in lipid metabolism and the onset of cardiovascular disease. In the present study, paraoxonase activities and phenotype distribution in serum of 132 healthy Iranian individuals aged 17-68 years were assessed using dual substrate method. In the study...
Topics
- Adolescent
- Adult
- Aged
- Aryldialkylphosphatase
- Carboxylic Ester Hydrolases
- Cholesterol
- Female
- Genetics, Population
- Humans
- Iran
- Male
- Middle Aged
- Phenotype
- Smoking
- Triglycerides
