Article
Generation of stomach tissue from mouse embryonic stem cells.
Nature cell biology - 1 Aug 2015
Noguchi Taka-aki K, Ninomiya Naoto, Sekine Mari, Komazaki Shinji, Wang Pi-Chao, Asashima Makoto, Kurisaki Akira
Abstract excerpt
Successful pluripotent stem cell differentiation methods have been developed for several endoderm-derived cells, including hepatocytes, β-cells and intestinal cells. However, stomach lineage commitment from pluripotent stem cells has remained a challenge, and only antrum specification has been demonstrated. We established a method for stomach differentiation from embryonic stem cells by inducing mesenchymal...
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