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The critical role of BMP signaling in gastric epithelial cell differentiation revealed by organoids

16 May 2025

Abstract excerpt

The efficient differentiation of adult gastric stem cells into specific epithelial cell types is crucial for gastric homeostasis. Although it is well appreciated that the niche plays a critical role in gastric epithelium cell differentiation, the relevant molecular factors and the underlying regulatory mechanisms remain poorly understood. In this study, by combining the knowledge of the niche cells obtained from...

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PMID: 40377813
DOI: 10.1186/s13619-025-00237-x

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