Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SIRT6/NF-κB signaling axis in ginsenoside Rg1-delayed hematopoietic stem/progenitor cell senescence.

International journal of clinical and experimental pathology - 1 Jan 2015

Tang Yan-Long, Zhou Yue, Wang Ya-Ping, Wang Jian-Wei, Ding Ji-Chao

Abstract excerpt

OBJECTIVE: To investigate the role of SIRT6/NF-κB signaling axis in ginsenoside Rg1-delayed hematopoietic stem/progenitor cell senescence and to provide theoretical and experimental evidence for delaying HSC/HPC senescence pathway. METHODS: After the separation and purification by immunomagnetic sorting, Sca-1+HSC/HPC was divided into: normal control group; aging group; positive control group; Rg1 delaying group...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Ly
Share to beta-Galactosidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Cellular Senescence

Share to G1 Phase Cell Cycle Checkpoints

Share to Hematopoietic Stem Cells

Share to NF-kappa B

Share to Sirtuin 1

Source

Open in PubMed Open full text

Identifiers

PMID: 26191269
PMCID: PMC4503140

Genes

SIRT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SIRT6/NF-κB signaling axis in ginsenoside Rg1-delayed hematopoietic stem/progenitor cell senescence.PMID 26191269Read ↗

Senescence as A Consequence of Ginsenoside Rg1Response on K562 Human Leukemia Cell LineSemantic proximity Read ↗

Secretion of IL-6 and IL-8 in the senescence of bone marrow mesenchymal stem cells is regulated by autophagy via FoxO3aSemantic proximity Read ↗

Nicotinamide riboside intervention alleviates hematopoietic system injury of ionizing radiation‐induced premature aging miceSemantic proximity Read ↗

Influence of aging on the activity of mice Sca-1+CD31- cardiac stem cells.Semantic proximity Read ↗

Ginsenoside Rb1 Relieves Cellular Senescence and Pulmonary Fibrosis by Promoting NRF2/QKI/SMAD7 AxisSemantic proximity Read ↗

hPMSCs protects against D-galactose-induced oxidative damage of CD4+ T cells through activating Akt-mediated Nrf2 antioxidant signaling Semantic proximity Read ↗

Radiation-induced premature cellular senescence involved in glomerular diseases in ratsSemantic proximity Read ↗

Autophagy‐Sirt3 axis decelerates hematopoietic agingSemantic proximity Read ↗

Downregulation of Sirt6 by CD38 promotes cell senescence and agingSemantic proximity Read ↗

PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosisSemantic proximity Read ↗

Inhibition of p16INK4A to Rejuvenate Aging Human Cardiac Progenitor Cells via the Upregulation of Anti-oxidant and NFκB Signal PathwaysSemantic proximity Read ↗

Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.