Back to search

Article

hPMSCs protects against D-galactose-induced oxidative damage of CD4+ T cells through activating Akt-mediated Nrf2 antioxidant signaling 

2020-10-26

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Mesenchymal stem cells (MSCs) was considered as regenerative therapeutic approach in both acute and chronic diseases. However, whether MSCs regulate the antioxidant metabolism of CD4<sup>+</sup> T cells and weaken immunosenescence remains unclear. Here, we reported the protective effects of hPMSCs in aging-related CD4<sup>+</sup> T cell senescence and identified...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7e1c1ac9-6e63-5ea5-a5cc-a5d23ff03425
DOI
10.21203/rs.3.rs-46702/v3
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
hPMSCs protects against D-galactose-induced oxidative damage of CD4+ T cells through activating Akt-mediated Nrf2 antioxidant signaling&nbsp;DOI 10.21203/rs.3.rs-46702/v3
Ameliorative Effects of Mesenchymal Stem Cells on Senescence Associated Phenotypes in Naturally Aged RatsSemantic proximity
Ameliorative effects of mesenchymal stromal cells on senescence associated phenotypes in naturally aged rats.Semantic proximity
HPMSCs Inhibit the Expression of PD-1 in CD4+IL-10+ T Cells and Mitigate liver Damage in a GVHD Mouse Model by Regulating the Cross-talk Between Nrf2 and NF-κB Signaling PathwaySemantic proximity
Application of mesenchymal stem cells for anti-senescence and clinical challengesSemantic proximity
Ellagic acid reveals promising anti-aging effects against d-galactose-induced aging on human neuroblastoma cell line, SH-SY5Y: A mechanistic studySemantic proximity
The CCL7-CCL2-CCR2 Axis Regulates Age-Related Alterations in ADSCs&nbsp;Semantic proximity
Effects of Oxidative Stress on Mesenchymal Stem Cell BiologySemantic proximity
Sirt3 Attenuates Oxidative Stress Damage and Rescues Cellular Senescence in Rat Bone Marrow Mesenchymal Stem Cells by Targeting Superoxide Dismutase 2Semantic proximity
Decreased miR-17-92 Cluster Correlates With the Senescent Features and Disrupted Oxidative Homeostasis, and the Impaired Therapeutic Efficacy of Adipose Tissue-derived Mesenchymal Stem CellsSemantic proximity
Cellular Senescence and Senescence-Associated Secretory Phenotype Drive Multipotent Cardiac Stem/Progenitor Cell Dysfunction in Human Diabetic Cardiomyopathy Independently of AgeSemantic proximity
Involvement of 8-O-acetylharpagide for Ajuga taiwanensis mediated suppression of senescent phenotypes in human dermal fibroblasts.Semantic proximity
Oxidative stress contributes to accelerated development of the senescent phenotype in human peritoneal mesothelial cells exposed to high glucose.Semantic proximity
Select a neighboring publication to make it the new centre.