Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri.

Fish & shellfish immunology - 1 Sept 2018

Liu Shan, Zheng Zhaodi, Ji Shuhua, Liu Tingting, Hou Yanhan, Li Shasha, Li Guorong

Abstract excerpt

Senescent cells display a senescence-associated secretory phenotype (SASP), which contributes to aging. Resveratrol, an activator of SIRT1, has anti-aging, anti-inflammatory, anti-oxidant, anti-free radical and other pharmacological effects. The genus of the annual fish Nothobranchius has become an emerging animal model for studying aging. However, the underlying mechanism for resveratrol to delay aging by SASP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Galactosidase
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyprinodontiformes

Share to Intestinal Mucosa

Share to Intestines

Share to Resveratrol

Share to Sirtuin 1

Share to Stilbenes

Source

Identifiers

PMID: 29908321
DOI: 10.1016/j.fsi.2018.06.027

Genes

SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri.PMID 29908321Read ↗

Resveratrol and the Pharmacology of Aging: A New Vertebrate Model to Validate an Old MoleculeSemantic proximity Read ↗

Knockout of longevity gene Sirt1 in zebrafish leads to oxidative injury, chronic inflammation, and reduced life spanSemantic proximity Read ↗

Resveratrol extends lifespan and preserves glia but not neurons of the Nothobranchius guentheri optic tectumSemantic proximity Read ↗

Nothobranchius as a model for anorexia of aging research: an evolutionary, anatomical, histological, immunohistochemical, and molecular studySemantic proximity Read ↗

Epigallocatechin Gallate Effectively Affects Senescence and Anti-SASP via SIRT3 in 3T3-L1 Preadipocytes in Comparison with Other Bioactive Substances.Semantic proximity Read ↗

SIRT6/NF-κB signaling axis in ginsenoside Rg1-delayed hematopoietic stem/progenitor cell senescence.Semantic proximity Read ↗

Resveratrol drives cancer cell senescence <i>via</i> enhancing p38MAPK and DLC1 expressionsSemantic proximity Read ↗

Nuciferine promotes longevity and fitness in Caenorhabditis elegans through the regulation of the insulin/IGF-1 signaling pathwaySemantic proximity Read ↗

Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cellsSemantic proximity Read ↗

Reversal of myoblast aging by tocotrienol rich fraction posttreatment.Semantic proximity Read ↗

Nicotinamide Riboside and Phycocyanin Oligopeptides Affect Stress Susceptibility in Chronic Corticosterone-Exposed RatsSemantic proximity Read ↗

Age-related morphological and functional changes in the small intestine of senescence-accelerated mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.