Article

PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosis

2022-04-15

Abstract excerpt

<title>Abstract</title> <p>Background: Stem cell senescence and depletion are major causes of organismal aging and aging-related diseases. The NAD–SIRT1–PARP1 axis has garnered remarkable interest owing to its significant role in regulating stem cell senescence and organismal aging. Event though our recent study showes that PBX1 overexpression attenuates hair follicle-derived mesenchymal stem cell (HF-MSC) senesc...

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Literature Corpus work: 5d2cd7df-e9a4-59d1-a236-5df379e4889a
DOI: 10.21203/rs.3.rs-1545647/v1

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