Article
Domain analysis of the Nematostella vectensis SNAIL ortholog reveals unique nucleolar localization that depends on the zinc-finger domains.
Scientific reports - 20 Jul 2015
Dattoli Ada A, Hink Mark A, DuBuc Timothy Q, Teunisse Bram J, Goedhart Joachim, Röttinger Eric, Postma Marten
Abstract excerpt
SNAIL transcriptional factors are key regulators during development and disease. They arose early during evolution, and in cnidarians such as Nematostella vectensis, NvSNAILA/B are detected in invaginating tissues during gastrulation. The function of SNAIL proteins is well established in bilaterians but their roles in cnidarians remain unknown. The structure of NvSNAILA and B is similar to the human SNAIL1 and 2,...
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