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Article

Biophysical subsets of embryonic stem cells display distinct phenotypic and morphological signatures.

PloS one - 1 Jan 2018

Bongiorno Tom, Gura Jeremy, Talwar Priyanka, Chambers Dwight, Young Katherine M, Arafat Dalia, Wang Gonghao, Jackson-Holmes Emily L, Qiu Peng, McDevitt Todd C, Sulchek Todd

Abstract excerpt

The highly proliferative and pluripotent characteristics of embryonic stem cells engender great promise for tissue engineering and regenerative medicine, but the rapid identification and isolation of target cell phenotypes remains challenging. Therefore, the objectives of this study were to characterize cell mechanics as a function of differentiation and to employ differences in cell stiffness to select...

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Identifiers

PMID: 29518080
DOI: 10.1371/journal.pone.0192631
PMCID: PMC5843178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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