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Article

Comprehensive molecular profiling of intrahepatic cholangiocarcinoma in the Chinese population and therapeutic experience.

Journal of translational medicine - 6 Jul 2020

Wang Longrong, Zhu Hongxu, Zhao Yiming, Pan Qi, Mao Anrong, Zhu Weiping, Zhang Ning, Lin Zhenhai, Zhou Jiamin, Wang Yilin, Zhang Yongfa, Wang Miao, Feng Yun, He Xigan, Xu Weiqi, Wang Lu

Abstract excerpt

BACKGROUND: The genomic alterations of intrahepatic cholangiocarcinoma (ICC) in the Chinese population have not been fully revealed. Molecular profiling may provide a reference for clinical management, especially targeted therapy. METHODS: A retrospective study was conducted in 122 ICC patients. All patients' samples underwent next-generation sequencing (NGS), which analyzed 417 genes. The genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32631434
DOI: 10.1186/s12967-020-02437-2
PMCID: PMC7336472

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