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High resolution melting analysis of the NR1I3 genetic variants: Is there an association with neonatal hyperbilirubinemia?

Gene - 1 Dec 2015

Cheung Tian Pei, Van Rostenberghe Hans, Ismail Rosliza, Nawawi Noor Namirah, Abdullah Nurul Amierah, Ramli Noraida, Ibrahim Nor Rosidah, Hj Abd Majid Noorizan, Mohd Yusoff Narazah, Nishio Hisahide, Yusoff Surini

Abstract excerpt

Constitutive androstane receptor (CAR) encoded by the nuclear receptor subfamily 1, group I, member 3 (NR1I3) gene regulates the elimination of bilirubin through activating the components of the bilirubin clearance pathway. Hence, NR1I3 genetic variants may affect bilirubin metabolism and result in neonatal hyperbilirubinemia. Thus far, research which investigates the association between NR1I3 variants and...

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PMID: 26188155
DOI: 10.1016/j.gene.2015.07.045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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