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Article

Newborn dried blood-spot screening of the p.V37I variant of GJB2 by high-resolution melting analysis.

International journal of pediatric otorhinolaryngology - 1 Jul 2014

Chen Ying, Li Lei, Sun Lian-hua, Yang Tao, Wu Hao

Abstract excerpt

OBJECTIVES: To establish a high-throughput, low-cost method for neonatal genetic testing of the p.V37I of GJB2 gene, which is highly prevalent in East Asians and strongly associated with postnatal childhood hearing impairment. METHODS: A total of 6460 newborn blood-spot DNA samples were screened by high-resolution melting analysis (HRMA). RESULTS: The screening results were further verified by direct sequencing...

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Identifiers

PMID: 24814571
DOI: 10.1016/j.ijporl.2014.04.009

Genes

GJB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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