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Article

Diagnosis of ABCB11 gene mutations in children with intrahepatic cholestasis using high resolution melting analysis and direct sequencing.

Molecular medicine reports - 1 Sept 2014

Hu Guorui, He Ping, Liu Zhifeng, Chen Qian, Zheng Bixia, Zhang Qihua

Abstract excerpt

Intrahepatic cholestasis represents a heterogeneous group of disorders that begin during childhood, most commonly manifesting as neonatal cholestasis, and lead to ongoing liver dysfunction in children and adults. For children, inherited pathogenic factors of cholestasis have gained increasing attention owing to the rapid development of molecular biology technology. However, these methods have their advantages and...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24969679
DOI: 10.3892/mmr.2014.2349
PMCID: PMC4121405

Genes

ABCB11

Provenance

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