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Article

Association of DNA repair genes polymorphisms with childhood acute lymphoblastic leukemia: a high-resolution melting analysis.

BMC research notes - 14 Feb 2022

Zehtab Shahrzad, Sattarzadeh Bardsiri Mahla, Mirzaee Khalilabadi Roohollah, Ehsan Mohsen, Fatemi Ahmad

Abstract excerpt

OBJECTIVE: Acute lymphoblastic leukemia (ALL) is one of the most common cancers in children for which the exact pathogenesis is not yet known. Single-nucleotide variants (SNVs) in different DNA repair genes are reported to be associated with ALL risk. This study aimed to determine the association between XRCC1 (rs1799782) and NBN (rs1805794, rs709816) SNVs and childhood ALL risk in a sample of the Iranian...

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Identifiers

PMID: 35164849
DOI: 10.1186/s13104-022-05918-3
PMCID: PMC8842869

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