Article
Copy Number Variations in CTNNA3 and RBFOX1 Associate with Pediatric Food Allergy.
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2015
Li Jin, Fung Irene, Glessner Joseph T, Pandey Rahul, Wei Zhi, Bakay Marina, Mentch Frank D, Pellegrino Renata, Wang Tiancheng, Kim Cecilia, Hou Cuiping, Wang Fengxiang, Chiavacci Rosetta M, Thomas Kelly A, Spergel Jonathan M, Hakonarson Hakon, Sleiman Patrick M A
Abstract excerpt
Food allergy is a significant public health concern, especially among children. Previous candidate gene studies suggested a few susceptibility loci for food allergy, but no study investigated the contribution of copy number variations (CNVs) to food allergy on a genome-wide scale. To investigate the genetics of food allergy, we performed CNV assessment using high-resolution genome-wide single nucleotide...
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