Article
Genetic association and identification of a functional SNP at GSK3β for schizophrenia susceptibility.
Schizophrenia research - 1 Dec 2011
Li Ming, Mo Yin, Luo Xiong-jian, Xiao Xiao, Shi Lei, Peng Ying-mei, Qi Xue-bin, Liu Xing-yan, Yin Li-de, Diao Hong-bo, Su Bing
Abstract excerpt
OBJECTIVE: GSK3β is a key gene in neurodevelopment, and also an important target of antipsychotics. Several lines of evidence including association and gene expression studies have suggested GSK3β as a susceptibility gene for schizophrenia, but the underlying genetic mechanism is still unknown. In this study, we test whether the genetic variants in GSK3β contribute to the risk of schizophrenia in Chinese...
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