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Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish

17 Jul 2015

Abstract excerpt

Mitochondrial flash (mitoflash) is a highly-conserved, universal, and physiological mitochondrial activity in isolated mitochondria, intact cells, and live organisms. Here we investigated developmental and disease-related remodeling of mitoflash activity in zebrafish skeletal muscles. In transgenic zebrafish expressing the mitoflash reporter cpYFP, in vivo imaging revealed that mitoflash frequency and unitary...

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PMID: 26186000
DOI: 10.1371/journal.pone.0132567

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