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Article

From SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathways.

BMC bioinformatics - 27 Aug 2009

Bauer-Mehren Anna, Furlong Laura I, Rautschka Michael, Sanz Ferran

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) are the most frequent type of sequence variation between individuals, and represent a promising tool for finding genetic determinants of complex diseases and understanding the differences in drug response. In this regard, it is of particular interest to study the effect of non-synonymous SNPs in the context of biological networks such as cell signalling pathways....

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PMID: 19758470
DOI: 10.1186/1471-2105-10-S8-S6
PMCID: PMC2745588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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