Article
The antineoplastic properties of FTY720: evidence for the repurposing of fingolimod.
Journal of cellular and molecular medicine - 1 Oct 2015
Patmanathan Sathya Narayanan, Yap Lee Fah, Murray Paul G, Paterson Ian C
Abstract excerpt
Almost all drugs approved for use in humans possess potentially beneficial 'off-target' effects in addition to their principal activity. In some cases this has allowed for the relatively rapid repurposing of drugs for other indications. In this review we focus on the potential for re-purposing FTY720 (also known as fingolimod, Gilenya(™)), an immunomodulatory drug recently approved for the treatment of multiple...
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