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Fyn Kinase in Brain Diseases and Cancer: The Search for Inhibitors

1 Jun 2011

Abstract excerpt

Fyn is a non-receptor tyrosine kinase belonging to the Src family kinases. It has been shown to play important roles in neuronal functions, including myelination and oligodendrocytes formation, and in inflammatory processes. It has also demonstrated its involvement in signaling pathways that lead to severe brain pathologies, such as Alzheimer's and Parkinson's diseases. Moreover, Fyn is upregulated in some...

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PMID: 21651487
DOI: 10.2174/092986711796150531

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