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Article

Nuclear Receptor Nur77 Attenuates Airway Inflammation in Mice by Suppressing NF-κB Activity in Lung Epithelial Cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2015

Kurakula Kondababu, Vos Mariska, Logiantara Adrian, Roelofs Joris J, Nieuwenhuis Maartje A, Koppelman Gerard H, Postma Dirkje S, van Rijt Leonie S, de Vries Carlie J M

Abstract excerpt

Allergic asthma is characterized by persistent chronic airway inflammation, which leads to mucus hypersecretion and airway hyperresponsiveness. Nuclear receptor Nur77 plays a pivotal role in distinct immune and inflammatory cells and is expressed in eosinophils and lung epithelium. However, the role of Nur77 in allergic airway inflammation has not been studied so far. In the present study, we determined the role...

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Identifiers

PMID: 26170382
DOI: 10.4049/jimmunol.1401714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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