Article
Computer-Assisted Transgenesis of Caenorhabditis elegans for Deep Phenotyping.
Genetics - 1 Sept 2015
Gilleland Cody L, Falls Adam T, Noraky James, Heiman Maxwell G, Yanik Mehmet F
Abstract excerpt
A major goal in the study of human diseases is to assign functions to genes or genetic variants. The model organism Caenorhabditis elegans provides a powerful tool because homologs of many human genes are identifiable, and large collections of genetic vectors and mutant strains are available. However, the delivery of such vector libraries into mutant strains remains a long-standing experimental bottleneck for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
