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Article

NeuroPAL: A Multicolor Atlas for Whole-Brain Neuronal Identification in C. elegans.

Cell - 7 Jan 2021

Yemini Eviatar, Lin Albert, Nejatbakhsh Amin, Varol Erdem, Sun Ruoxi, Mena Gonzalo E, Samuel Aravinthan D T, Paninski Liam, Venkatachalam Vivek, Hobert Oliver

Abstract excerpt

Comprehensively resolving neuronal identities in whole-brain images is a major challenge. We achieve this in C. elegans by engineering a multicolor transgene called NeuroPAL (a neuronal polychromatic atlas of landmarks). NeuroPAL worms share a stereotypical multicolor fluorescence map for the entire hermaphrodite nervous system that resolves all neuronal identities. Neurons labeled with NeuroPAL do not exhibit...

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Identifiers

PMID: 33378642
DOI: 10.1016/j.cell.2020.12.012
PMCID: PMC10494711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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