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Article

SOX9 is a regulator of ADAMTSs-induced cartilage degeneration at the early stage of human osteoarthritis

8 Jul 2015

Abstract excerpt

OBJECTIVE: To identify whether cartilage master regulator SRY-related protein 9 (SOX9) mediates A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) dysregulation during osteoarthritis (OA) cartilage degeneration. METHOD: Twenty-two randomly selected OA patients were evaluated using Outerbridge Classification via arthroscopy. Haematoxylin-eosin (HE), Safranin O and Masson staining were...

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PMID: 26162802
DOI: 10.1016/j.joca.2015.06.014

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