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Article

The role of ADAMTSs in arthritis

1 Jan 2010

Abstract excerpt

The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family consists of 19 proteases. These enzymes are known to play important roles in development, angiogenesis and coagulation; dysregulation and mutation of these enzymes have been implicated in many disease processes, such as inflammation, cancer, arthritis and atherosclerosis. This review briefly summarizes the structural organization...

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PMID: 21203996
DOI: 10.1007/s13238-010-0002-5

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The role of ADAMTSs in arthritisPMID 21203996Read ↗

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Evolutionary divergence and functions of the ADAM and ADAMTS gene familiesSemantic proximity Read ↗

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